Takopii no Genzai | タコピーの原罪 | Octopii's Original Sin | Octoppi's Original Sin | Le péché originel de Takopi | Nguyên Tội Của Takopi | Первородний гріх Такопі | Первородный грех Такопи | Takopi eredendő bűne | Takopi's Original Sin | El pecado original de Takopi | O Pecado Original de Takopi | Takopis Sündenfall | 타코피의 원죄 | Takopi no Genzai (Official Colored)

Takopi's Original Sin (Japanese: タコピーの原罪, Hepburn: Takopī no Genzai) is a Japanese web manga series written and illustrated by Taizan 5. It was published on Shueisha's web platform Shōnen Jump+ from December 2021 to March 2022, with its chapters collected in two tankōbon volumes. An original net animation (ONA) adaptation produced by Enishiya and TBS Television was released from June to August 2025.

A guest from the planet of happiness, the alien Takopi, arrives on Earth to spread happiness throughout the Earth and meets Shizuka, a girl who never smiles. Looks like she has problems at school and with friends... What will the simple-minded Takopi face? An amazing story begins!